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Dr Senarath Edirimanne

Research and Education

As a senior lecturer at University of Sydney, Dr. Edirimanne is actively involved in research, teaching and educational activities. He is currently undertaking his doctorate at University of Sydney.

Research interests:

Breast Cancer:

  • Epidemiology
  • Translational research
  • Surgical techniques and outcomes including oncoplastic and immediate breast reconstruction
  • Breast cancer survivorship
  • Outcomes of treatment, patient quality of life and psychosocial wellbeing

Endocrine Surgery:

  • Thyroid cancer epidemiology
  • Epidemiology and Etiology of autoimmune thyroid disease and associated opthalmopathy
  • Primary hyperparathyroidism

General Surgery:

  • Emergency surgical models of delivery and outcomes

Research collaborations/Associations:

  • Whitely- Martin Research Unit, Nepean Clinical School, University of Sydney
  • Endocrine, Haematology and Geriatrics Research Units, Nepean Clinical School, University of Sydney
  • Sydney West Translational Cancer research Centre

Post-graduate research Supervision:

Completed:

  1. Prudence L Hardefeldt, Metformin and breast cancer risk, Honours Project, University of Sydney 2013
  2. Prudence J Hardefeldt, The effect of benign thyroid disease, diabetes mellitus, weight loss and physical activity on breast cancer risk, Master of Philosophy, University of Sydney, 2013

Current:

  1. Dr. Kyle Joseph, Master of Philosophy, University of Sydney
  2. Dr. Kenneth Brito, Master of Surgery, University of Sydney

Publications:

  1. Lahooti, H., Cultrone, D., Edirimanne, S. Walsh, J., Delbridge, L., Cregan, P., El Kochairi, I., Champion, B., Wall, J. (2014), Association of the CASQ1 Gene SNP rs3838216 with Graves’ opthalmopathy and Hashimoto’s Thyroiditis in patients with thyroid autoimmunity. Opthalmology Research., 2(6): 281-293.
  2. Cultrone, D., Lahooti, H., Edirimanne, S., Delbridge, L., Champion, B., Wall, J. (2014), Calsequestrin is decreased in thyroid gland of patients with Graves’ disease- Further evidence for a role of autoimmunity against this protein in Graves’ opthalmopathy. British Journal of Medicine and Medical Research., 4(23): 4065-4075.
  3. Hardefeldt, P., Edirimanne, S., Eslick, G. (2013), Goiter is Associated with Benign Breast Disease: A Meta-Analysis. The Breast Journal.19(3), 346-468. [Abstract]
  4. Hardefeldt, P., Edirimanne, S., Eslick, G. (2013), Deodorant use and breast cancer risk. Epidemiology. 24(1), 172. [Abstract]
  5. Hardefeldt, P., Edirimanne, S., Eslick, G. (2012), Diabetes increases the risk of breast cancer: a meta-analysis. Endocrine-Related Cancer. 19(6), 793-803. [Abstract]
  6. Hardefeldt, P., Edirimanne, S., Eslick, G. (2012), Deodorant use and the risk of skin toxicity in patients undergoing radiation therapy for breast cancer: A meta-analysis. Radiotherapy & Oncology. 105(3), 378-379.[Abstract]
  7. Watts KJ, Meiser B, Mitchell G, Kirk J, Saunders C, Peate M, Duffy J, Kelly PJ, Gleeson M, Barlow-Stewart K, Rahman B, Friedlander M, Tucker K; TFGT Collaborative Group. (2012) How should we discuss genetic testing with women newly diagnosed with breast cancer? Design and implementation of a randomized controlled trial of two models of delivering education about treatment-focused genetic testing to younger women newly diagnosed with breast cancer. BMC Cancer. 2012 Jul 28;12:320.
  8. Hardefeldt, P., Eslick, G., Edirimanne, S. (2012), Benign thyroid disease is associated with breast cancer: a meta-analysis. Breast Cancer Research and Treatment. 133(3), 1169-1177. [Abstract]
  9. Parnaby, C., Barrow, E., Edirimanne, S., Parrott, N., Frizelle, F., Watson, A. (2010), Colorectal complications of end-stage renal failure and renal transplantation: a review. Colorectal Disease Online. 14(4), 403–415. [Abstract]
  10. Edirimanne, S., Roake, J., Lewis, D. (2010), Delays in discharge of vascular surgical patients: a prospective audit. ANZ Journal of Surgery 80(6), 443-446. [Abstract]
  11. Edirimanne, S., Connor, S. (2008), Incidental pancreatic cystic lesions. World Journal of Surgery. 32(9), 2028-2037. [Abstract]
  12. Edirimanne, S., McKenzie, K., Wells, S., Dijkstra, B., (2007), Role of pre-operative breast MRI in patients with invasive lobular carcinoma of breast. ANZ Journal of Surgery. 77, s1 A3
  13. Edirimanne, S., Dunn, S. (2005), Sentinel node biopsy for breast cancer using patent blue dye only localization by a regional general surgeon. ANZ Journal of Surgery. 75, A98-99
  14. Edirimanne, S., Gao, J., Clements, J., Nicol ,D. (2005), Effects of PSA on expression of insulin like growth factor system and osteoblastic markers in prostate cancer cell line PC-3 and osteoblast like cell line SAOS. ANZ Journal of Surgery . 75(7) A129-134

Presentations

  1. Joseph, K, Eslick, G, Edirimanne, S. On the association between primary Breast Cancer and Thyroid Cancer, RACS ASM, Singapore, 2014
  2. Meybodi,F. Wu, Y. Edirimanne, S. Eslick, G. Cox, M. Factors contributing to delays in patient discharge after an acute surgical admission, ISW, Helsinki,2013
  3. Brito, K. Edirimanne, S. Eslick, G. The extent of improvement of health-related quality of life after parathyroidectomy in patients with primary hyperparathyroidism- A systematic review and meta-analysis. ISW, Helsinki 2013 and RACS ASM , Auckland, 2013
  4. Staniforth, J. Edirimanne, S. Eslick, G. Thyroid Cancer in Graves’ disease- A meta-analysis, ISW, Helsinki 2013
  5. Sedaghat, N. Edirimanne, S. Eslick, G. Morbidity of chemotherapy and Immediate breast reconstruction: A systematic review and Meta-analysis. . ISW, Helsinki 2013 and RACS ASM , Auckland, 2013
  6. Sedaghat, N. Edirimanne, S. Eslick, G. Morbidity of adjuvant radiotherapy and immediate breast reconstruction: A systematic review and Meta-analysis. . ISW, Helsinki 2013 and RACS ASM , Auckland, 2013
  7. Nagaraja, V. Edirimanne, S. Eslick, G. Recurrence and functional outcomes of partial adrenalectomy: A systematic review and Meta-analysis. . ISW, Helsinki 2013 and RACS ASM Auckland, 2013
  8. Wu, Y. Edirimanne, S. Eslick, G. Does surgical resection of the primary tumour in patients presenting with systemic metastatic breast cancer improve overall survival? : A systematic review and Meta-analysis. . ISW, Helsinki 2013 and RACS ASM, Auckland, 2013
  9. Hardefeldt, P, Edirimanne, S. Eslick, G. Physical activity reduces risk of breast cancer, San Antonio Breast cancer Conference, USA, 2012
  10. Hardefeldt, P, Edirimanne, S. Eslick, G. Diabetes increases the risk of Breast Cancer. San Antonio Breast Cancer Conference, USA, 2012
  11. Wu, Y. Edirimanne, S. Tiver, K. Cheung, D. Fuller, S. Radiotherapy for breast cancer associated with cutaneous presentation of systemic mastocytosis- a case report and literature review- Sydney International Breast Cancer Conference 2012
  12. Azmir, A. Edirimanne, S. French, J. Boyages J. Elder E. Surgical management of low volume sentinel node positive axilla- Is a tailored approach suitable?. Surgical Research Society ASM, Adelaide, 2012.
  13. Nagaraja, V. Edirimanne, S. Eslick, G. Is sentinel node biopsy necessary in patients undergoing prophylactic mastectomy? : A systematic review and Meta-analysis. GSA ASM, Horbart, 2012
  14. Hardefeldt, P, Edirimanne, S. Eslick, G. Benign thyroid disease is associated with breast cancer – A meta analysis. San Antonio Breast Cancer Conference, USA, 2011

National guidelines:

  1. Management of central nervous system (CNS) metastases in women with secondary breast cancer. (2014). Cancer Australia